• About
    ▼
    • Overview
    • Leadership
    • Our Team
    • Board of Directors
    • Investors
  • Science
    ▼
    • Overview
    • Highly Cytotoxic T Cells
    • KLRG1
    • Publications
  • Pipeline
    ▼
    • Overview
    • ABC008
    • IBM
    • T-LGLL
    • Additional Indications
    • ABC015
  • News
  • Careers
  • Contact
About

About

Abcuro

Breakthrough Therapies for Autoimmune Diseases & Cancer

  • About
    • Overview
    • Leadership
    • Our Team
    • Board of Directors
    • Investors
  • Science
    • Overview
    • Highly Cytotoxic T Cells
    • KLRG1
    • Publications
  • Pipeline
    • Overview
    • ABC008
    • IBM
    • T-LGLL
    • Additional Indications
    • ABC015
  • News
  • Careers
  • Contact

About

LEADERSHIP

OUR TEAM

BOARD OF DIRECTORS

INVESTORS

Selective Targeting of Highly Cytotoxic T Cells in Autoimmune Diseases

Abcuro is developing its lead product candidate ABC008 for autoimmune disorders. ABC008 is a monoclonal antibody designed to selectively deplete highly cytotoxic T cells by targeting killer cell lectin-like receptor G1 (KLRG1), a marker selectively expressed on these highly cytotoxic T cells.

In autoimmune diseases such as inclusion body myositis (IBM), cytotoxic T cells are a major source of chronic tissue damage. In November 2021, we presented initial results from a Phase 1 open-label trial of ABC008 in IBM at American College of Rheumatology Convergence 2021 (view poster) and an updated dataset was presented at GCOM 2022 (view poster). In this trial, ABC008 demonstrated potent depletion of KLRG1+ T cells in patients with IBM.

In cancer, inhibition of KLRG1, an inhibitory immune checkpoint not targeted by any of the currently available therapies, can activate highly cytotoxic T and natural killer (NK) cells and leverage their potent anti-tumor activity. Abcuro is advancing ABC015, a KLRG1-blocking antibody through preclinical development for immune-oncology applications.

View Pipeline

Martin, Alex

September 29, 2022

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA

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Alex Martin

Chief Executive Officer

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Alex Martin

Chief Executive Officer

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA Pharma (EPIX). He was also Chief Operating Officer of Intercept Pharmaceuticals (ICPT), and Chief Finance Officer of BioXell (BXLN) which was acquired by Cosmo Pharmaceuticals (COPN). He began his career at SmithKline Beecham Pharmaceuticals where he held roles of increasing responsibility in marketing and business development and later joined Novartis as Vice President, Global Business Development & Licensing. Alex is an active coach and mentor to other senior executives, and a guest lecturer at Wharton and Columbia Business School on biotech, entrepreneurship, and raising capital. He holds a BA from Cornell University and an MBA from Harvard

Greenberg, Steven A.

September 7, 2021

Steven A Greenberg, M.D., M.S. is a founder of Abcuro and is the Chair of the Medical Advisory Board. Steve is a clinical neurologist at Brigham and Women’s Hospital, and Professor of Neurology at Harvard Medical School. His clinical and laboratory research focus involves translational medicine, inventing diagnostics including blood tests for dermatomyositis and inclusion

 READ MORE

Steven A. Greenberg, MD

Chief Scientific Advisor and
Chair, Medical Advisory Board

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Steven A. Greenberg, MD

Chief Scientific Advisor and
Chair, Medical Advisory Board

Steven A Greenberg, M.D., M.S. is a founder of Abcuro and is the Chair of the Medical Advisory Board. Steve is a clinical neurologist at Brigham and Women’s Hospital, and Professor of Neurology at Harvard Medical School. His clinical and laboratory research focus involves translational medicine, inventing diagnostics including blood tests for dermatomyositis and inclusion body myositis, and therapeutics, including co-inventing a therapeutic monoclonal antibody for dermatomyositis currently in late-stage clinical trials. He has authored over 100 publications and served as Principal Investigator for multiple clinical trials. Steve received an A.B. degree in Mathematics from Princeton University, an M.S. degree in Medical Informatics from Massachusetts Institute of Technology, and an M.D. degree from Harvard Medical School through the Harvard-MIT Health Science and Technology Program.

Wilkins, Jeffrey

June 13, 2022

Jeffrey Wilkins is the Chief Medical Officer of Abcuro. He is a highly experienced clinician, having advanced clinical programs from IND to regulatory approval. Jeff has deep expertise in the areas of immunology, rare diseases, and immuno-oncology. He has served in senior clinical leadership positions, including as Chief Medical Officer for over 20 years. Among

 READ MORE

H. Jeffrey Wilkins, MD

Chief Medical Officer

x

H. Jeffrey Wilkins, MD

Chief Medical Officer

Jeffrey Wilkins is the Chief Medical Officer of Abcuro. He is a highly experienced clinician, having advanced clinical programs from IND to regulatory approval. Jeff has deep expertise in the areas of immunology, rare diseases, and immuno-oncology. He has served in senior clinical leadership positions, including as Chief Medical Officer for over 20 years. Among others, Jeff led clinical development programs at Avalo Therapeutics, Lycera, Ceptaris Therapeutics, Cephalon, and Ception Therapeutics. He entered the pharmaceutical industry with GlaxoSmithKline, where he rose to become Vice President of Discovery Medicine for GSK’s Center of Excellence in External Drug Discovery. Jeff received his M.D. from Temple University School of Medicine and his B.S. from Bucknell University.

Tubridy, Karen

December 13, 2022

Karen Tubridy is the Chief Development Officer of Abcuro.  She brings more than 30 years of experience in drug development strategy and operations supporting novel and first-in-class therapeutics.  Previously, Karen served as a Chief Development Officer at Verseau Therapeutics, Akebia Therapeutics, and Eleven Bio.  She has had responsibility for driving global program strategies to IND,

 READ MORE

Karen Tubridy

Chief Development Officer

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Karen Tubridy

Chief Development Officer

Karen Tubridy is the Chief Development Officer of Abcuro.  She brings more than 30 years of experience in drug development strategy and operations supporting novel and first-in-class therapeutics.  Previously, Karen served as a Chief Development Officer at Verseau Therapeutics, Akebia Therapeutics, and Eleven Bio.  She has had responsibility for driving global program strategies to IND, NDA and J-NDA filings.  In addition, she has had responsibility for oversight of drug development operations including the build out of core R&D infrastructure and quality systems. Previously, she held senior positions in clinical and regulatory operations at Inspiration Biopharmaceuticals, Taligen Therapeutics (acquired by Alexion) and Syntonix Pharmaceuticals (acquired by Biogen).  She held a senior position at AVANT Immunotherapeutics directing several vaccine programs and held positions of increasing responsibility in clinical research and medical affairs at Genetics Institute/Wyeth Pharmaceuticals, where she directed hematology and oncology programs.  Karen holds a B.S. in pharmacy and a PharmD from the Massachusetts College of Pharmacy and Allied Health Sciences.

Subramanyam, Janaki

May 20, 2022

Janaki (Jana) Subramanyam is Vice President, Head of Regulatory Affairs at Abcuro. Jana is an experienced regulatory affairs professional having worked on small molecule and biologic development programs across rheumatology, nephrology, neurology, and psychiatry for more than twenty years. Her regulatory drug development expertise spans clinical, nonclinical, manufacturing, quality, post marketing advertising, and promotional activities.

 READ MORE

Janaki M. Subramanyam

VP, Head of Regulatory Affairs

x

Janaki M. Subramanyam

VP, Head of Regulatory Affairs

Janaki (Jana) Subramanyam is Vice President, Head of Regulatory Affairs at Abcuro. Jana is an experienced regulatory affairs professional having worked on small molecule and biologic development programs across rheumatology, nephrology, neurology, and psychiatry for more than twenty years. Her regulatory drug development expertise spans clinical, nonclinical, manufacturing, quality, post marketing advertising, and promotional activities. Prior to joining Abcuro, Jana was the Head of Regulatory Affairs at Allena Pharmaceuticals, Inc. where she helped develop two assets for rare metabolic diseases. Jana also held leadership roles in regulatory affairs at FORUM Pharmaceuticals, Lantheus Medical Imaging, and AMAG Pharmaceuticals. She received her M.S. in microbiology from Ohio University and her B.S. in microbiology and biochemistry from Bombay Universit

Anderson, Jeff

March 7, 2022

Jeff Anderson

Office Manager

x

Jeff Anderson

Office Manager

Borbas, Dave

March 7, 2022

Dave Borbas

Research VP,
Head of Data Management

x

Dave Borbas

Research VP,
Head of Data Management

Chartienitz, Brett

March 7, 2022

Brett Chartienitz

IT Operations Manager

x

Brett Chartienitz

IT Operations Manager

Cooper, Ken

August 29, 2022

Ken Cooper

Clinical Operations, Trial Management

x

Ken Cooper

Clinical Operations, Trial Management

Deware, Patricia

September 7, 2021

Patricia Deware

VP, Finance and Planning

x

Patricia Deware

VP, Finance and Planning

Edwards, John

September 7, 2021

John Edwards brings over 30 years of experience in discovery, development, and global commercialization of biopharmaceuticals. He was involved in the development or commercialization of ten FDA-approved biologics and has had successful exits at eight of the ten biotech companies he helped to build, including Tilos Therapeutics, Siamab Therapeutics, Exonics Therapeutics, Adnexus Therapeutics, F-star Therapeutics,

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John Edwards

Executive Chair

x

John Edwards

Executive Chair

John Edwards brings over 30 years of experience in discovery, development, and global commercialization of biopharmaceuticals. He was involved in the development or commercialization of ten FDA-approved biologics and has had successful exits at eight of the ten biotech companies he helped to build, including Tilos Therapeutics, Siamab Therapeutics, Exonics Therapeutics, Adnexus Therapeutics, F-star Therapeutics, and Genetics Institute. He built a hematology therapeutic business that reached over $1 billion in annual revenue for Wyeth/Genetics Institute and was responsible for leading the development of the fastest biologic to progress from phase I to FDA approval. John started his career in research and development as one of the first employees at Genzyme. He received his M.B.A. from Boston University and his B.S. in Chemical Engineering from the University of Massachusetts at Amherst.

Greenberg, Steven A.

September 7, 2021

Steven A Greenberg, M.D., M.S. is a founder of Abcuro and is the Chair of the Medical Advisory Board. Steve is a clinical neurologist at Brigham and Women’s Hospital, and Professor of Neurology at Harvard Medical School. His clinical and laboratory research focus involves translational medicine, inventing diagnostics including blood tests for dermatomyositis and inclusion

 READ MORE

Steven A. Greenberg, MD

Chief Scientific Advisor and
Chair, Medical Advisory Board

x

Steven A. Greenberg, MD

Chief Scientific Advisor and
Chair, Medical Advisory Board

Steven A Greenberg, M.D., M.S. is a founder of Abcuro and is the Chair of the Medical Advisory Board. Steve is a clinical neurologist at Brigham and Women’s Hospital, and Professor of Neurology at Harvard Medical School. His clinical and laboratory research focus involves translational medicine, inventing diagnostics including blood tests for dermatomyositis and inclusion body myositis, and therapeutics, including co-inventing a therapeutic monoclonal antibody for dermatomyositis currently in late-stage clinical trials. He has authored over 100 publications and served as Principal Investigator for multiple clinical trials. Steve received an A.B. degree in Mathematics from Princeton University, an M.S. degree in Medical Informatics from Massachusetts Institute of Technology, and an M.D. degree from Harvard Medical School through the Harvard-MIT Health Science and Technology Program.

Gress, Mike

September 1, 2022

Mike Gress

VP, Clinical Development,
Head of Clinical Trial Management

x

Mike Gress

VP, Clinical Development,
Head of Clinical Trial Management

Hoffer, LaDonna

March 7, 2022

LaDonna Hoffer

Senior Director, Operations

x

LaDonna Hoffer

Senior Director, Operations

Hwang, Ella

May 9, 2022

Ella Hwang

Senior Director, Quality

x

Ella Hwang

Senior Director, Quality

Jiang, Lusi

March 7, 2022

Lusi Jiang

Senior Accountant

x

Lusi Jiang

Senior Accountant

LeMessurier, Hugo

March 7, 2022

Hugo LeMessurier

Director, Abcuro Pty Ltd

x

Hugo LeMessurier

Director, Abcuro Pty Ltd

Martin, Alex

September 29, 2022

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA

 READ MORE

Alex Martin

Chief Executive Officer

x

Alex Martin

Chief Executive Officer

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA Pharma (EPIX). He was also Chief Operating Officer of Intercept Pharmaceuticals (ICPT), and Chief Finance Officer of BioXell (BXLN) which was acquired by Cosmo Pharmaceuticals (COPN). He began his career at SmithKline Beecham Pharmaceuticals where he held roles of increasing responsibility in marketing and business development and later joined Novartis as Vice President, Global Business Development & Licensing. Alex is an active coach and mentor to other senior executives, and a guest lecturer at Wharton and Columbia Business School on biotech, entrepreneurship, and raising capital. He holds a BA from Cornell University and an MBA from Harvard

McClain, Michael

March 7, 2022

Michael McClain

Clinical Trial Manager

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Michael McClain

Clinical Trial Manager

Motschwiller, Ricky

March 7, 2022

Richard Motschwiller

Controller

x

Richard Motschwiller

Controller

Reyes, Armando

March 31, 2022

Armando Reyes

Associate Clinical Director

x

Armando Reyes

Associate Clinical Director

Rozzo, Aldo

March 7, 2022

Aldo Rozzo, PhD, DVM

Lab Manager

x

Aldo Rozzo, PhD, DVM

Lab Manager

Searle, Stephen

May 20, 2022

Stephen A. Searle

Senior Program Manager

x

Stephen A. Searle

Senior Program Manager

Shen, Yuyi

April 4, 2022

Yuyi Shen, PhD

VP, Technical Operations

x

Yuyi Shen, PhD

VP, Technical Operations

Soler-Ferran, Dulce, PhD

March 7, 2022

Dulce Soler-Ferran, PhD

VP, Biology

x

Dulce Soler-Ferran, PhD

VP, Biology

Subramanyam, Janaki

May 20, 2022

Janaki (Jana) Subramanyam is Vice President, Head of Regulatory Affairs at Abcuro. Jana is an experienced regulatory affairs professional having worked on small molecule and biologic development programs across rheumatology, nephrology, neurology, and psychiatry for more than twenty years. Her regulatory drug development expertise spans clinical, nonclinical, manufacturing, quality, post marketing advertising, and promotional activities.

 READ MORE

Janaki M. Subramanyam

VP, Head of Regulatory Affairs

x

Janaki M. Subramanyam

VP, Head of Regulatory Affairs

Janaki (Jana) Subramanyam is Vice President, Head of Regulatory Affairs at Abcuro. Jana is an experienced regulatory affairs professional having worked on small molecule and biologic development programs across rheumatology, nephrology, neurology, and psychiatry for more than twenty years. Her regulatory drug development expertise spans clinical, nonclinical, manufacturing, quality, post marketing advertising, and promotional activities. Prior to joining Abcuro, Jana was the Head of Regulatory Affairs at Allena Pharmaceuticals, Inc. where she helped develop two assets for rare metabolic diseases. Jana also held leadership roles in regulatory affairs at FORUM Pharmaceuticals, Lantheus Medical Imaging, and AMAG Pharmaceuticals. She received her M.S. in microbiology from Ohio University and her B.S. in microbiology and biochemistry from Bombay Universit

Tubridy, Karen

December 13, 2022

Karen Tubridy is the Chief Development Officer of Abcuro.  She brings more than 30 years of experience in drug development strategy and operations supporting novel and first-in-class therapeutics.  Previously, Karen served as a Chief Development Officer at Verseau Therapeutics, Akebia Therapeutics, and Eleven Bio.  She has had responsibility for driving global program strategies to IND,

 READ MORE

Karen Tubridy

Chief Development Officer

x

Karen Tubridy

Chief Development Officer

Karen Tubridy is the Chief Development Officer of Abcuro.  She brings more than 30 years of experience in drug development strategy and operations supporting novel and first-in-class therapeutics.  Previously, Karen served as a Chief Development Officer at Verseau Therapeutics, Akebia Therapeutics, and Eleven Bio.  She has had responsibility for driving global program strategies to IND, NDA and J-NDA filings.  In addition, she has had responsibility for oversight of drug development operations including the build out of core R&D infrastructure and quality systems. Previously, she held senior positions in clinical and regulatory operations at Inspiration Biopharmaceuticals, Taligen Therapeutics (acquired by Alexion) and Syntonix Pharmaceuticals (acquired by Biogen).  She held a senior position at AVANT Immunotherapeutics directing several vaccine programs and held positions of increasing responsibility in clinical research and medical affairs at Genetics Institute/Wyeth Pharmaceuticals, where she directed hematology and oncology programs.  Karen holds a B.S. in pharmacy and a PharmD from the Massachusetts College of Pharmacy and Allied Health Sciences.

Ward, Antonio

March 7, 2022

Antonio Ward, PhD

Senior Scientist

x

Antonio Ward, PhD

Senior Scientist

Weems Gary

August 6, 2022

Garry Weems

VP, Clinical Science

x

Garry Weems

VP, Clinical Science

Wilkins, Jeffrey

June 13, 2022

Jeffrey Wilkins is the Chief Medical Officer of Abcuro. He is a highly experienced clinician, having advanced clinical programs from IND to regulatory approval. Jeff has deep expertise in the areas of immunology, rare diseases, and immuno-oncology. He has served in senior clinical leadership positions, including as Chief Medical Officer for over 20 years. Among

 READ MORE

H. Jeffrey Wilkins, MD

Chief Medical Officer

x

H. Jeffrey Wilkins, MD

Chief Medical Officer

Jeffrey Wilkins is the Chief Medical Officer of Abcuro. He is a highly experienced clinician, having advanced clinical programs from IND to regulatory approval. Jeff has deep expertise in the areas of immunology, rare diseases, and immuno-oncology. He has served in senior clinical leadership positions, including as Chief Medical Officer for over 20 years. Among others, Jeff led clinical development programs at Avalo Therapeutics, Lycera, Ceptaris Therapeutics, Cephalon, and Ception Therapeutics. He entered the pharmaceutical industry with GlaxoSmithKline, where he rose to become Vice President of Discovery Medicine for GSK’s Center of Excellence in External Drug Discovery. Jeff received his M.D. from Temple University School of Medicine and his B.S. from Bucknell University.

Edwards, John

September 7, 2021

John Edwards brings over 30 years of experience in discovery, development, and global commercialization of biopharmaceuticals. He was involved in the development or commercialization of ten FDA-approved biologics and has had successful exits at eight of the ten biotech companies he helped to build, including Tilos Therapeutics, Siamab Therapeutics, Exonics Therapeutics, Adnexus Therapeutics, F-star Therapeutics,

 READ MORE

John Edwards

Executive Chair

x

John Edwards

Executive Chair

John Edwards brings over 30 years of experience in discovery, development, and global commercialization of biopharmaceuticals. He was involved in the development or commercialization of ten FDA-approved biologics and has had successful exits at eight of the ten biotech companies he helped to build, including Tilos Therapeutics, Siamab Therapeutics, Exonics Therapeutics, Adnexus Therapeutics, F-star Therapeutics, and Genetics Institute. He built a hematology therapeutic business that reached over $1 billion in annual revenue for Wyeth/Genetics Institute and was responsible for leading the development of the fastest biologic to progress from phase I to FDA approval. John started his career in research and development as one of the first employees at Genzyme. He received his M.B.A. from Boston University and his B.S. in Chemical Engineering from the University of Massachusetts at Amherst.

Martin, Alex

September 29, 2022

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA

 READ MORE

Alex Martin

Chief Executive Officer

x

Alex Martin

Chief Executive Officer

Alex Martin brings over 30 years of experience building companies and closing transactions in the biopharmaceutical industry. He was most recently Chief Executive Officer of Palladio Biosciences, a clinical stage biopharmaceutical company which was acquired by Centessa Pharmaceuticals (CNTA), and previously served as Chief Executive Officer of Realm Therapeutics (RLM) which was acquired by ESSA Pharma (EPIX). He was also Chief Operating Officer of Intercept Pharmaceuticals (ICPT), and Chief Finance Officer of BioXell (BXLN) which was acquired by Cosmo Pharmaceuticals (COPN). He began his career at SmithKline Beecham Pharmaceuticals where he held roles of increasing responsibility in marketing and business development and later joined Novartis as Vice President, Global Business Development & Licensing. Alex is an active coach and mentor to other senior executives, and a guest lecturer at Wharton and Columbia Business School on biotech, entrepreneurship, and raising capital. He holds a BA from Cornell University and an MBA from Harvard

Knowles, Julius (Jay)

March 7, 2022

Jay Knowles joined Mass General Brigham Ventures in 2014 as a Partner. Previously, Jay was Chief Executive Officer of X-BODY Biosciences, which was acquired by Juno Therapeutics.  Prior to X-BODY, he was at Novartis in charge of the Platforms team for Strategic Alliances, responsible for global technology and drug discovery collaborations. Jay was also President

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Julius (Jay) Knowles

Partner, Mass General Brigham Ventures

x

Julius (Jay) Knowles

Partner, Mass General Brigham Ventures

Jay Knowles joined Mass General Brigham Ventures in 2014 as a Partner. Previously, Jay was Chief Executive Officer of X-BODY Biosciences, which was acquired by Juno Therapeutics.  Prior to X-BODY, he was at Novartis in charge of the Platforms team for Strategic Alliances, responsible for global technology and drug discovery collaborations. Jay was also President of Novalar Pharmaceuticals, Vice President of Business Development at Novacea, and Director, R&D Planning at Vertex Pharmaceuticals. He represents Mass General Brigham Ventures on the boards of Apres Therapeutics, Keros Therapeutics, SwanBio Therapeutics, and Triplet Therapeutics. Jay earned his M.B.A in Finance from Wharton Business School, an M.Sc. in Chemistry from UC Berkeley, and a B.A. with Distinction in Chemistry from Carleton College.

Hafler, Jason P. , PhD

March 7, 2022

Jason P. Hafler is the Managing Director of Sanofi Ventures. Prior to joining Sanofi in 2014, Jason was the Director of Corporate Development at RaNA Therapeutics, a company co-founded by his previous firm Atlas Venture. While at Atlas, Jason was an Associate in the Life Sciences group. Previously, he was a Flagship Ventures Entrepreneurial Fellow,

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Jason P. Hafler, PhD

Managing Director, Sanofi Ventures

x

Jason P. Hafler, PhD

Managing Director, Sanofi Ventures

Jason P. Hafler is the Managing Director of Sanofi Ventures. Prior to joining Sanofi in 2014, Jason was the Director of Corporate Development at RaNA Therapeutics, a company co-founded by his previous firm Atlas Venture. While at Atlas, Jason was an Associate in the Life Sciences group. Previously, he was a Flagship Ventures Entrepreneurial Fellow, and consulted for the technology transfer company at the University of Cambridge while performing his doctoral research. Before his time at Cambridge, Jason was an analyst at JSB Partners LP, an investment banking firm.  Jason’s active investments include Abcuro, Amathus Therapeutics, Escient Pharmaceuticals, Expansion Therapeutics, Glycomine, Q32 Bio, ReCode Therapeutics, Rome Therapeutics and Navitor Pharmaceuticals. Jason graduated with honors from Bowdoin College and holds a Ph.D. from the University of Cambridge.

Kariv, Tomer

March 8, 2023

Tomer is the co-founder and Chief Executive Officer of Pontifax. He serves as an active board member of many of the funds’ portfolio companies, assuming a special responsibility for strategic planning. Among other positions, Tomer serves as the chairman at Eloxx Pharmaceuticals, board member in Cathworks, Keros Therapeutics, Ocon Healthcare, ARMGO and V-Wave. During the

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Tomer Kariv

Co-Founder and Chief Executive Officer, Pontifax

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Tomer Kariv

Co-Founder and Chief Executive Officer, Pontifax

Tomer is the co-founder and Chief Executive Officer of Pontifax. He serves as an active board member of many of the funds’ portfolio companies, assuming a special responsibility for strategic planning. Among other positions, Tomer serves as the chairman at Eloxx Pharmaceuticals, board member in Cathworks, Keros Therapeutics, Ocon Healthcare, ARMGO and V-Wave. During the 10 years prior to establishing Pontifax, he held senior management positions at top Israeli financial institutions, playing a key role in investing in, nurturing and managing technology-driven startups. Tomer holds a B.A. in Economics from Harvard University and a J.D. from Harvard Law School.

Shah, Rajeev

March 7, 2022

Rajeev Shah has been a Managing Partner at RA Capital Management since 2004. Raj is active in both public and private investments in companies developing drugs, medical devices, diagnostics, and research tools. He is also active in the firm’s outreach efforts, speaking frequently both at industry events and in classrooms.  He previously worked as a

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Rajeev Shah

Managing Partner, RA Capital Management

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Rajeev Shah

Managing Partner, RA Capital Management

Rajeev Shah has been a Managing Partner at RA Capital Management since 2004. Raj is active in both public and private investments in companies developing drugs, medical devices, diagnostics, and research tools. He is also active in the firm’s outreach efforts, speaking frequently both at industry events and in classrooms.  He previously worked as a Senior Project Leader at Altus Pharmaceuticals, a spin-off company of Vertex Pharmaceuticals, where he assessed business processes and implemented system solutions across all areas of science. Rajeev is currently a member of the board of directors of the public companies Solid Biosciences, Black Diamond Therapeutics and Satsuma Pharmaceuticals, as well as of a number of private biotechnology companies. He holds a B.A. from Cornell University, where he majored in Chemistry.

McCarthy, Donnie

October 27, 2022

Donald McCarthy is Vice President at Samsara Biocapital. Prior to joining Samsara, he was a Partner at Global Founders Capital where he founded and invested in multiple therapeutics companies. Previously, Donald served as a Senior Fellow in Entrepreneurship at Life Science Angels where he helped source and evaluate new deals and was a Managing Director

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Donnie McCarthy, PhD

Vice President, Samsara BioCapital

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Donnie McCarthy, PhD

Vice President, Samsara BioCapital

Donald McCarthy is Vice President at Samsara Biocapital. Prior to joining Samsara, he was a Partner at Global Founders Capital where he founded and invested in multiple therapeutics companies. Previously, Donald served as a Senior Fellow in Entrepreneurship at Life Science Angels where he helped source and evaluate new deals and was a Managing Director at Panorama Research, where he oversaw the strategy and development of several wholly owned subsidiaries. In addition, he was an Advisor to KCK Group, where he provided diligence for potential investments in therapeutics companies. He holds a PhD in Immunology and Biochemistry from the State University of New York in Albany. He did his postdoctoral fellowship at the Cardiovascular Research Institute at UCSF. Following his fellowship, Donnie co-founded Empire Biotechnologies, a GI therapeutics company, and AMP Biotech Research, a research group providing diligence to public investors.

Deptula-Hicks, Darlene

March 7, 2022

Ms. Deptula-Hicks currently serves as F-star’s Chief Financial Officer. In addition, Darlene has operated Crimson Advisors, a strategic and financial consulting services company, and has served as acting Chief Financial Officer for Northern Biologics as well Senior Vice President and Chief Financial Officer of T2 Biosystems. Previously she was Senior Vice President and Chief Financial

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Darlene Deptula-Hicks

Chief Financial Officer,
F-star Therapeutics

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Darlene Deptula-Hicks

Chief Financial Officer,
F-star Therapeutics

Ms. Deptula-Hicks currently serves as F-star’s Chief Financial Officer. In addition, Darlene has operated Crimson Advisors, a strategic and financial consulting services company, and has served as acting Chief Financial Officer for Northern Biologics as well Senior Vice President and Chief Financial Officer of T2 Biosystems. Previously she was Senior Vice President and Chief Financial Officer of Pieris Pharmaceuticals and Vice President and Chief Financial Officer of Microline Surgical.  Darlene currently also serves on the board of directors and as audit committee chair of Aerami Therapeutics and previously served on the board of directors and as audit committee chair of Giner Life Sciences, Xentic Biosciences, and IMCOR Pharmaceuticals. Darlene received an M.B.A. from Rivier University and a B.S in Accounting from Southern New Hampshire University.

Berger, Dietmar

May 20, 2022

Dietmar Berger is currently the Chief Medical Officer and Head of Global Development at Sanofi, where he oversees the clinical portfolio of Sanofi across all therapeutic areas. With over 20 years of experience in leadership positions across both large pharmaceutical companies as well as innovative biotech companies, Dr. Berger brings extensive expertise in clinical development

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Dietmar Berger, MD, PhD

Observer, Chief Medical Officer
and Head of Global Development at Sanofi

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Dietmar Berger, MD, PhD

Observer, Chief Medical Officer
and Head of Global Development at Sanofi

Dietmar Berger is currently the Chief Medical Officer and Head of Global Development at Sanofi, where he oversees the clinical portfolio of Sanofi across all therapeutic areas. With over 20 years of experience in leadership positions across both large pharmaceutical companies as well as innovative biotech companies, Dr. Berger brings extensive expertise in clinical development and advancing programs all the way to market approval to Abcuro. As a trained hematologist and oncologist, Dr. Berger  has extensive experience in therapeutic areas of high relevance to Abcuro’s programs. Prior to Sanofi, he was Global Head of R&D at Atara Biotherapeutics, an off-the-shelf cell therapy company. Previously he held senior positions in clinical development at Amgen, Bayer and Genentech where he served as the Senior Vice President of Global Clinical Development, Hematology/Oncology. Dr. Berger holds an M.D. and Ph.D. from the Albert-Ludwigs University School of Medicine in Freiburg, Germany, where he still maintains an adjunct faculty position.

Xu, Yajun

June 20, 2022

Yajun Xu is currently president of Hongsen Investment Group. She also serves as Senior Advisor for Shangbay Capital, co-founder of Epimab, and board member and advisor on numerous biotech companies in U.S. and China. Previously, she was Senior Vice President of Corporate Development at Shangpharma, Executive Vice President of Biology and Pre-Clinical Service at Chempartner

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Yajun Xu, PhD

Observer, President, Hongsen

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Yajun Xu, PhD

Observer, President, Hongsen

Yajun Xu is currently president of Hongsen Investment Group. She also serves as Senior Advisor for Shangbay Capital, co-founder of Epimab, and board member and advisor on numerous biotech companies in U.S. and China. Previously, she was Senior Vice President of Corporate Development at Shangpharma, Executive Vice President of Biology and Pre-Clinical Service at Chempartner in Shanghai, China. Prior to Joining Shangpharma, Yajun was Director of Inflammation at Millennium Pharmaceuticals and Senior Scientist at BASF Bioresearch (now AbbVie Bioresearch). She received her Ph.D. in Biochemistry at Brandeis University and postdoctoral training at Harvard School of Public Health.

Hongsen Investment

September 17, 2021

Mass General Brigham Ventures

September 17, 2021

Pontifax

September 17, 2021

RA Capital

September 17, 2021

Samsara Biocapital

September 17, 2021

Sanofi Ventures

September 17, 2021

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